Profhilo vs Jalupro vs Nucleofill: which skin booster is right for me?

A simple guide by Dr Adriana M. Ozery, Doctor Picasso, Limassol

Skin boosters are injectable treatments that improve the quality of your skin itself: hydration, firmness, elasticity and glow. They do not change the shape of your face like fillers do. Profhilo, Jalupro Super Hydro and Nucleofill are three of the most popular, and each works in a different way.

Profhilo: deep hydration and firmness

Profhilo contains a high concentration of pure hyaluronic acid that spreads evenly under the skin. It deeply hydrates, improves firmness and gives a fresh, radiant look. It is a great choice for dehydrated skin and early skin laxity on the face and neck. A course is usually two sessions about four weeks apart, followed by maintenance. Profhilo Structura is a newer version designed to support the mid and lower face.

Jalupro Super Hydro: hydration plus building blocks

Jalupro Super Hydro combines hyaluronic acid with amino acids and peptides, the building blocks your skin uses to make collagen and elastin. It helps with dehydration, fine lines, loss of firmness and tired-looking skin. It is usually given as a course of three to four sessions, two to four weeks apart.

Nucleofill: repair and regeneration

Nucleofill is based on polynucleotides, which support the skin’s natural repair processes. It improves elasticity, thickness and texture, and is especially helpful for thin, tired or damaged skin. Nucleofill Soft Plus is designed for the delicate under-eye area, while Nucleofill Strong and Strong Plus treat deeper layers. It is usually given as a short course every two to three weeks.

So which one is right for me?

In simple terms: Profhilo for deep hydration and firmness, Jalupro Super Hydro for hydration and fine lines, and Nucleofill for repair, elasticity and the under-eye area. Many patients benefit from combining them, which is why we created packages such as The Collagen Renewal Edit. The right choice depends on your skin, your age and your goals, so it is always decided together at your consultation.

Ready to start?

Book a consultation online on Fresha or send us a message on WhatsApp with any questions — Dr Adriana M. Ozery will be happy to advise you.

This article is general information and not a substitute for a personal medical consultation.

See our skin boosters · Packages · FAQ & Aftercare

Not sure which treatment is right for you?

Book a consultation and Dr Adriana M. Ozery will assess your skin and create a personalised plan around your goals.

Book on Fresha →